FAQ-011: Why did LI-RADS change the LR-5 criteria?
To achieve congruency with the new AASLD criteria released in 2018.
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FAQ-012: How will this affect the specificity of LR-5 for diagnosis of HCC?
The revised criteria are slightly less stringent; some specificity reduction is expected. The reduction is likely to be small, however, as prior studies have shown that in high-risk patients, the combination of 10-19 mm size, nonrim APHE, and nonperipheral “washout” provides > 90% specificity for HCC.
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FAQ-013: Why did LI-RADS eliminate the –us and –g designations?
For simplicity and based on feedback from international users that the designations are irrelevant outside the United States and introduce unnecessary complexity.
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FAQ-014: Why did LI-RADS v2018 change the definition of threshold growth?
For simplicity and concordance with AASLD and OPTN criteria.
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FAQ-015: How does the change in definition impact the characterization of growth?
The impact on categorization is summarized below:
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FAQ-016: How do the changes introduced in v2018 impact categorization?
The impact on categorization is summarized below:
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FAQ-017: I am a radiologist at a transplant center in the USA. What are the key differences between LI-RADS 5 and OPTN Class 5?
There is only one substantive difference between LI-RADS 5 and OPTN Class 5:
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FAQ-018: What are other differences?
Other differences relate to nomenclature. For example:
